Uroplakin 3A anticorps (AA 260-279) (CF®740)

N° du produit ABIN7661693

L’anticorps Lapin Polyclonal anti-Uroplakin 3A a été validé pour WB. Il convient pour détecter Uroplakin 3A dans des échantillons de Humain.

Aperçu rapide pour Uroplakin 3A anticorps (AA 260-279) (CF®740) (ABIN7661693)

Antigène: Uroplakin 3A (UPK3A)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Uroplakin 3A est conjugé à/à la CF®740

Application: Western Blotting (WB)

Détail du produit anti-Uroplakin 3A anticorps (CF®740)

Épitope: AA 260-279

Fonction: UPK3A (Uroplakin 3A)(Rabbit PAb), CF740 conjugate

Attributs du produit: Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A

Isotype: IgG

Information d'application

Indications d'application: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 1-2 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user

Commentaires:

Positive Control: HEK293 cells or bladder carcinoma

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur Uroplakin 3A

Antigène: Uroplakin 3A (UPK3A)

Autre désignation: UPK3A

Sujet:

Synonyms: UP3a, UPIIIA, UPK3A, Uroplakin III (UPIII), Uroplakin3A

Gene Symbol: UPK3A

Tissue Expression: Urothelial cells

Poids moléculaire: ~30 kDa

ID gène: 7380

UniProt: O75631